TCF7_HUMAN P36402
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UniProt:P36402
Recommended name:Transcription factor 7
EC number:
Alternative names:(TCF-7) (T-cell-specific transcription factor 1) (T-cell factor 1) (TCF-1)
Cleaved into:
GeneID:6932
Gene names (primary ):TCF7
Gene names (synonym ):TCF1
Gene names (ORF ):
Length:384
Mass:41642
Sequence:MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTETNWPRELKDGNGQESLSMSSSSSPA
Tissue specificity:Predominantly expressed in T-cells. Also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. {ECO:0000269|PubMed:10489374}.
Induction:By TCF7L2 and CTNNB1. {ECO:0000269|PubMed:10489374}.
Developmental stage:
Protein families:TCF/LEF family