ASPN_HUMAN Q9BXN1
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UniProt:Q9BXN1
Recommended name：Asporin
EC number：
Alternative names：(Periodontal ligament-associated protein 1) (PLAP-1)
Cleaved into：
GeneID：54829
Gene names (primary )：ASPN
Gene names (synonym )：PLAP1 SLRR1C
Gene names (ORF )：UNQ215/PRO241
Length：380
Mass：43417
Sequence：MKEYVLLLFLALCSAKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPTREPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNFGM
Tissue specificity：Higher levels in osteoarthritic articular cartilage, aorta, uterus. Moderate expression in small intestine, heart, liver, bladder, ovary, stomach, and in the adrenal, thyroid, and mammary glands. Low expression in trachea, bone marrow, and lung. Colocalizes with TGFB1 in chondrocytes within osteoarthritic (OA) lesions of articular cartilage. {ECO:0000269|PubMed:17827158}.
Induction：By TGFB1. {ECO:0000269|PubMed:17827158}.
Developmental stage：
Protein families：Small leucine-rich proteoglycan (SLRP) family, SLRP class I subfamily