ARHG8_HUMAN Q7Z628
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UniProt:Q7Z628
Recommended name：Neuroepithelial cell-transforming gene 1 protein
EC number：
Alternative names：(Proto-oncogene p65 Net1) (Rho guanine nucleotide exchange factor 8)
Cleaved into：
GeneID：10276
Gene names (primary )：NET1
Gene names (synonym )：ARHGEF8
Gene names (ORF )：
Length：596
Mass：67740
Sequence：MEPELAAQKQPRPRRRSRRASGLSTEGATGPSADTSGSELDGRCSLRRGSSFTFLTPGPNWDFTLKRKRREKDDDVVSLSSLDLKEPSNKRVRPLARVTSLANLISPVRNGAVRRFGQTIQSFTLRGDHRSPASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGELRSKSGHKLYIFLFQDILVLTRPVTRNERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRIRFHDPSPAQSHTLQANDVFHKQQWFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRASTVSSVTQVEVDENAYRCGSGMQMAEDSKSLKTHQTQPGIRRARDKALSGGKRKETLV
Tissue specificity：Widely expressed. {ECO:0000269|PubMed:8649828}.
Induction：By TGFB1. Up-regulated by DNA damaging agents like H(2)O(2) or ionizing radiation (IR). {ECO:0000269|PubMed:11278519, ECO:0000269|PubMed:21373644}.
Developmental stage：
Protein families：