TFB2M_HUMAN   Q9H5Q4


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UniProt:Q9H5Q4

Recommended name:Dimethyladenosine transferase 2, mitochondrial

EC number:EC:2.1.1.-

Alternative names:(Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)

Cleaved into:

GeneID:64216

Gene names  (primary ):TFB2M

Gene names  (synonym ):NS5ATP5

Gene names  (ORF ):

Length:396

Mass:45349

Sequence:MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR

Tissue specificity:Ubiquitously expressed. {ECO:0000269|PubMed:12068295}.

Induction:By the nuclear respiratory factors NRF1 and NRF2/GABPB2 and PGC-1 coactivators. {ECO:0000269|PubMed:15684387}.

Developmental stage:

Protein families:Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family, KsgA subfamily


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