TFB2M_HUMAN Q9H5Q4
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UniProt:Q9H5Q4
Recommended name:Dimethyladenosine transferase 2, mitochondrial
EC number:EC:2.1.1.-
Alternative names:(Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)
Cleaved into:
GeneID:64216
Gene names (primary ):TFB2M
Gene names (synonym ):NS5ATP5
Gene names (ORF ):
Length:396
Mass:45349
Sequence:MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
Tissue specificity:Ubiquitously expressed. {ECO:0000269|PubMed:12068295}.
Induction:By the nuclear respiratory factors NRF1 and NRF2/GABPB2 and PGC-1 coactivators. {ECO:0000269|PubMed:15684387}.
Developmental stage:
Protein families:Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family, KsgA subfamily