EFNA1_HUMAN P20827
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UniProt:P20827
Recommended name:Ephrin-A1
EC number:
Alternative names:(EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4)
Cleaved into:Ephrin-A1, secreted form
GeneID:1942
Gene names (primary ):EFNA1
Gene names (synonym ):EPLG1 LERK1 TNFAIP4
Gene names (ORF ):
Length:205
Mass:23787
Sequence:MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIGHSAAPRLFPLAWTVLLLPLLLLQTP
Tissue specificity:Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level). {ECO:0000269|PubMed:17332925}.
Induction:By TNF and IL1B/interleukin-1 beta.
Developmental stage:
Protein families:Ephrin family