EFNA1_HUMAN   P20827


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UniProt:P20827

Recommended name:Ephrin-A1

EC number:

Alternative names:(EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4)

Cleaved into:Ephrin-A1, secreted form

GeneID:1942

Gene names  (primary ):EFNA1

Gene names  (synonym ):EPLG1 LERK1 TNFAIP4

Gene names  (ORF ):

Length:205

Mass:23787

Sequence:MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIGHSAAPRLFPLAWTVLLLPLLLLQTP

Tissue specificity:Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level). {ECO:0000269|PubMed:17332925}.

Induction:By TNF and IL1B/interleukin-1 beta.

Developmental stage:

Protein families:Ephrin family


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