KIN17_HUMAN O60870
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UniProt:O60870
Recommended name:DNA/RNA-binding protein KIN17
EC number:
Alternative names:(Binding to curved DNA) (KIN, antigenic determinant of recA protein homolog)
Cleaved into:
GeneID:22944
Gene names (primary ):KIN
Gene names (synonym ):BTCD KIN17
Gene names (ORF ):
Length:393
Mass:45374
Sequence:MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQEVPTFTELSRENDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEGIQYEDISKLA
Tissue specificity:Ubiquitously expressed in all tissues examined, with highest levels in skeletal muscle, heart and testis. Differentially expressed in non-tumorigenic and tumorigenic cell lines. Highly expressed in proliferating epithelial keratinocyte cells in vitro (at protein level). {ECO:0000269|PubMed:10964102, ECO:0000269|PubMed:9266022}.
Induction:By UVC irradiation in quiescent primary fibroblasts. By mitomycin C in human melanoma MeWO cells. {ECO:0000269|PubMed:10964102, ECO:0000269|PubMed:12525703}.
Developmental stage:
Protein families:KIN17 family