VASH1_HUMAN   Q7L8A9


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UniProt:Q7L8A9

Recommended name:Tubulinyl-Tyr carboxypeptidase 1

EC number:EC:3.4.17.17

Alternative names:(Tubulin carboxypeptidase 1) (Tyrosine carboxypeptidase 1) (TTCP 1) (Vasohibin-1)

Cleaved into:

GeneID:22846

Gene names  (primary ):VASH1

Gene names  (synonym ):KIAA1036 VASH

Gene names  (ORF ):

Length:365

Mass:40957

Sequence:MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNGYQIRV

Tissue specificity:Preferentially expressed in endothelial cells (PubMed:15467828, PubMed:16707096). Highly expressed in fetal organs (PubMed:15467828). Expressed in brain and placenta, and at lower level in heart and kidney (PubMed:15467828). Highly detected in microvessels endothelial cells of atherosclerotic lesions (PubMed:16707096). {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:16707096}.

Induction:By VEGF. {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:15649403}.

Developmental stage:

Protein families:Transglutaminase-like superfamily, Vasohibin family


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