VASH1_HUMAN Q7L8A9
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UniProt:Q7L8A9
Recommended name:Tubulinyl-Tyr carboxypeptidase 1
EC number:EC:3.4.17.17
Alternative names:(Tubulin carboxypeptidase 1) (Tyrosine carboxypeptidase 1) (TTCP 1) (Vasohibin-1)
Cleaved into:
GeneID:22846
Gene names (primary ):VASH1
Gene names (synonym ):KIAA1036 VASH
Gene names (ORF ):
Length:365
Mass:40957
Sequence:MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNGYQIRV
Tissue specificity:Preferentially expressed in endothelial cells (PubMed:15467828, PubMed:16707096). Highly expressed in fetal organs (PubMed:15467828). Expressed in brain and placenta, and at lower level in heart and kidney (PubMed:15467828). Highly detected in microvessels endothelial cells of atherosclerotic lesions (PubMed:16707096). {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:16707096}.
Induction:By VEGF. {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:15649403}.
Developmental stage:
Protein families:Transglutaminase-like superfamily, Vasohibin family