SKAP_HUMAN Q9Y448
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UniProt:Q9Y448
Recommended name:Small kinetochore-associated protein
EC number:
Alternative names:(SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (Kinetochore-localized astrin/SPAG5-binding protein) (TRAF4-associated factor 1)
Cleaved into:
GeneID:90417
Gene names (primary ):KNSTRN
Gene names (synonym ):C15orf23 SKAP TRAF4AF1
Gene names (ORF ):HSD11
Length:316
Mass:35438
Sequence:MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM
Tissue specificity:Widely expressed, including in skin. {ECO:0000269|PubMed:25194279}.
Induction:Degraded at the end of mitosis. Down-regulated upon exposure to nitric oxide. {ECO:0000269|PubMed:15855057, ECO:0000269|PubMed:22110139}.
Developmental stage:
Protein families: