MAPK5_HUMAN Q8IW41
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UniProt:Q8IW41
Recommended name：MAP kinase-activated protein kinase 5
EC number：EC:2.7.11.1
Alternative names：(MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (p38-regulated/activated protein kinase) (PRAK)
Cleaved into：
GeneID：8550
Gene names (primary )：MAPKAPK5
Gene names (synonym )：PRAK
Gene names (ORF )：
Length：473
Mass：54220
Sequence：MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDSVYIHDHENGAEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQEAWKYNRECKLLRDTLQSFSWNGRGFTDKVDRLKLAEIVKQVIEEQTTSHESQ
Tissue specificity：Expressed ubiquitously. {ECO:0000269|PubMed:9628874}.
Induction：Directly regulated by MYC: expression is activated by MYC, suggesting the existence of a feedback regulatory loop. {ECO:0000269|PubMed:21329882}.
Developmental stage：
Protein families：Protein kinase superfamily, CAMK Ser/Thr protein kinase family