ST17A_HUMAN Q9UEE5
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UniProt:Q9UEE5
Recommended name：Serine/threonine-protein kinase 17A
EC number：EC:2.7.11.1
Alternative names：(DAP kinase-related apoptosis-inducing protein kinase 1)
Cleaved into：
GeneID：9263
Gene names (primary )：STK17A
Gene names (synonym )：DRAK1
Gene names (ORF )：
Length：414
Mass：46558
Sequence：MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
Tissue specificity：Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9786912}.
Induction：Directly regulated by p53/TP53: induced following cisplatin treatment in a p53/TP53-dependent manner. p53/TP53 activates expression by directly binding to its regulatory regions. {ECO:0000269|PubMed:15940259, ECO:0000269|PubMed:21489989}.
Developmental stage：
Protein families：Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily