S38A1_HUMAN Q9H2H9
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UniProt:Q9H2H9
Recommended name：Sodium-coupled neutral amino acid transporter 1
EC number：
Alternative names：(Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1)
Cleaved into：
GeneID：81539
Gene names (primary )：SLC38A1
Gene names (synonym )：ATA1 NAT2 SAT1 SNAT1
Gene names (ORF )：
Length：487
Mass：54048
Sequence：MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSDEGH
Tissue specificity：Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. {ECO:0000269|PubMed:10891391, ECO:0000269|PubMed:12388062, ECO:0000269|PubMed:15054072, ECO:0000269|PubMed:16148032}.
Induction：Down-regulated by bacterial lipopolysaccharides (LPS) in glial cells. Down-regulated upon hypoxia. {ECO:0000269|PubMed:12388062, ECO:0000269|PubMed:16583402}.
Developmental stage：
Protein families：Amino acid/polyamine transporter 2 family