BABA2_HUMAN Q9NXR7
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UniProt:Q9NXR7
Recommended name：BRISC and BRCA1-A complex member 2
EC number：
Alternative names：(BRCA1-A complex subunit BRE) (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein)
Cleaved into：
GeneID：9577
Gene names (primary )：BABAM2
Gene names (synonym )：BRCC45 BRE
Gene names (ORF )：
Length：383
Mass：43552
Sequence：MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFVPQFQEAAFANGKL
Tissue specificity：Expressed in all cell lines examined. Highly expressed in placenta. {ECO:0000269|PubMed:11676476}.
Induction：Down-regulated by DNA-damaging agents in fibroblasts, by retinoic acid in brain glioma U-251MG and promyelocytic HL-60 cell lines, and by bacterial lipopolysaccharides (LPS) in peripheral blood mononuclear cells (PBMC). {ECO:0000269|PubMed:11676476, ECO:0000269|PubMed:7826398}.
Developmental stage：
Protein families：BABAM2 family