TRI41_HUMAN Q8WV44
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UniProt:Q8WV44
Recommended name:E3 ubiquitin-protein ligase TRIM41
EC number:EC:2.3.2.27
Alternative names:(RING finger-interacting protein with C kinase) (RINCK) (RING-type E3 ubiquitin transferase TRIM41) (Tripartite motif-containing protein 41)
Cleaved into:
GeneID:90933
Gene names (primary ):TRIM41
Gene names (synonym ):RINCK
Gene names (ORF ):
Length:630
Mass:71670
Sequence:MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELDREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP
Tissue specificity:Expressed in multiple tissues with the highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:17893151}.
Induction:Down-regulated by muramyl-dipeptide and lipopolysaccharide. {ECO:0000269|PubMed:27812135}.
Developmental stage:
Protein families:TRIM/RBCC family