TNF13_HUMAN O75888
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UniProt:O75888
Recommended name:Tumor necrosis factor ligand superfamily member 13
EC number:
Alternative names:(A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1)
Cleaved into:
GeneID:8741
Gene names (primary ):TNFSF13
Gene names (synonym ):APRIL TALL2 ZTNF2
Gene names (ORF ):UNQ383/PRO715
Length:250
Mass:27433
Sequence:MPASSPFLLAPKGPPGNMGGPVREPALSVALWLSWGAALGAVACAMALLTQQTELQSLRREVSRLQGTGGPSQNGEGYPWQSLPEQSSDALEAWENGERSRKRRAVLTQKQKKQHSVLHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSPHGTFLGFVKL
Tissue specificity:Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Induction:Down-regulated by phorbol myristate acetate/ionomycin treatment.
Developmental stage:
Protein families:Tumor necrosis factor family