ATF5_HUMAN Q9Y2D1
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q9Y2D1
Recommended name：Cyclic AMP-dependent transcription factor ATF-5
EC number：
Alternative names：(cAMP-dependent transcription factor ATF-5) (Activating transcription factor 5) (Transcription factor ATFx)
Cleaved into：
GeneID：22809
Gene names (primary )：ATF5
Gene names (synonym )：ATFX
Gene names (ORF )：
Length：282
Mass：30674
Sequence：MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC
Tissue specificity：Widely expressed with higher expression levels in liver. {ECO:0000269|PubMed:18332083}.
Induction：Down-regulated by pro-apoptotic stimuli (PubMed:21212266). However, the pro-apoptotic cisplatin increases protein levels by inhibiting polyubiquitination (PubMed:18458088). IL1B increases protein levels through protein stabilization and increase of translation efficiency (PubMed:24379400). {ECO:0000269|PubMed:18458088, ECO:0000269|PubMed:21212266, ECO:0000269|PubMed:24379400}.
Developmental stage：
Protein families：BZIP family