ZNT5_HUMAN Q8TAD4
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UniProt:Q8TAD4
Recommended name：Zinc transporter 5
EC number：
Alternative names：(ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1)
Cleaved into：
GeneID：64924
Gene names (primary )：SLC30A5
Gene names (synonym )：ZNT5 ZNTL1 ZTL1
Gene names (ORF )：UNQ863/PRO1879
Length：765
Mass：84047
Sequence：MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVGLFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSVDVGGAKRLQALSHLVSVLLLCPWVIVLSVTTESKVESWFSLIMPFATVIFFVMILDFYVDSICSVKMEVSKCARYGSFPIFISALLFGNFWTHPITDQLRAMNKAAHQESTEHVLSGGVVVSAIFFILSANILSSPSKRGQKGTLIGYSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHAHSHAHGASQGSCHSSDHSHSHHMHGHSDHGHGHSHGSAGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM
Tissue specificity：Ubiquitously expressed. Highly expressed in pancreas, liver and kidney. Expressed abundantly in insulin-containing beta cells, undetectable in other endocrine cell types including glucagon-secreting alpha cells and most acinar cells. {ECO:0000269|PubMed:11904301, ECO:0000269|PubMed:11937503}.
Induction：Down-regulated by ZNF658 in response to zinc. {ECO:0000269|PubMed:15276077, ECO:0000269|PubMed:25582195}.
Developmental stage：
Protein families：Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily