CL12A_HUMAN   Q5QGZ9


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UniProt:Q5QGZ9

Recommended name:C-type lectin domain family 12 member A

EC number:

Alternative names:(C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL) (CD antigen CD371)

Cleaved into:

GeneID:160364

Gene names  (primary ):CLEC12A

Gene names  (synonym ):CLL1 DCAL2 MICL

Gene names  (ORF ):

Length:265

Mass:30762

Sequence:MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVLASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKMANPVQLGSTYFREA

Tissue specificity:Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages. {ECO:0000269|PubMed:14739280, ECO:0000269|PubMed:15548716, ECO:0000269|PubMed:16239426, ECO:0000269|PubMed:16838277}.

Induction:Down-regulated in activated leukocytes recruited to a site of inflammation. {ECO:0000269|PubMed:16838277}.

Developmental stage:

Protein families:


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