CTNL1_HUMAN Q9UBT7
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UniProt:Q9UBT7
Recommended name：Alpha-catulin
EC number：
Alternative names：(Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)
Cleaved into：
GeneID：8727
Gene names (primary )：CTNNAL1
Gene names (synonym )：
Gene names (ORF )：
Length：734
Mass：81896
Sequence：MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNGWVSVTNKDTMDSKT
Tissue specificity：Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland. {ECO:0000269|PubMed:10542337, ECO:0000269|PubMed:12270917, ECO:0000269|PubMed:9806841}.
Induction：Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis. {ECO:0000269|PubMed:9806841}.
Developmental stage：
Protein families：Vinculin/alpha-catenin family