RAD_HUMAN   P55042


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UniProt:P55042

Recommended name:GTP-binding protein RAD

EC number:

Alternative names:(RAD1) (Ras associated with diabetes)

Cleaved into:

GeneID:6236

Gene names  (primary ):RRAD

Gene names  (synonym ):RAD

Gene names  (ORF ):

Length:308

Mass:33245

Sequence:MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAAAGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL

Tissue specificity:Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans. {ECO:0000269|PubMed:18056528}.

Induction:Down-regulated in failing hearts. {ECO:0000269|PubMed:18056528}.

Developmental stage:

Protein families:Small GTPase superfamily, RGK family


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