CAR16_HUMAN Q5EG05
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UniProt:Q5EG05
Recommended name:Caspase recruitment domain-containing protein 16
EC number:
Alternative names:(Caspase recruitment domain-only protein 1) (CARD-only protein 1) (Caspase-1 inhibitor COP) (Pseudo interleukin-1 beta converting enzyme) (Pseudo-ICE) (Pseudo-IL1B-converting enzyme)
Cleaved into:
GeneID:114769
Gene names (primary ):CARD16
Gene names (synonym ):COP COP1
Gene names (ORF ):
Length:197
Mass:22625
Sequence:MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQWLFLRTNFIERFWRNILLLPLHKGSLYPRIPGLGKELQTGTHKLS
Tissue specificity:Widely expressed. Expressed at higher level in placenta, spleen, lymph node and bone marrow. Weakly or not expressed in thymus. {ECO:0000269|PubMed:11432859, ECO:0000269|PubMed:11536016}.
Induction:Down-regulated in patients suffering of Huntington disease. {ECO:0000269|PubMed:16354923}.
Developmental stage:
Protein families: