SLPI_HUMAN   P03973


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UniProt:P03973

Recommended name:Antileukoproteinase

EC number:

Alternative names:(ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4)

Cleaved into:

GeneID:6590

Gene names  (primary ):SLPI

Gene names  (synonym ):WAP4 WFDC4

Gene names  (ORF ):

Length:132

Mass:14326

Sequence:MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA

Tissue specificity:Detected in blood plasma (PubMed:24352879). Detected in bone marrow myeloid cells (PubMed:24352879). Detected in airway sputum (PubMed:2039600). Detected in parotid gland secretions (PubMed:3462719). Detected in seminal plasma (at protein level) (PubMed:3485543). Detected in uterus cervix (PubMed:3533531). {ECO:0000269|PubMed:2039600, ECO:0000269|PubMed:24352879, ECO:0000269|PubMed:3462719, ECO:0000269|PubMed:3485543, ECO:0000269|PubMed:3533531}.

Induction:Down-regulated in response to low ELANE activity. Up-regulated by ELANE treatment in bone marrow cells. {ECO:0000269|PubMed:24352879}.

Developmental stage:

Protein families:


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