NSUN5_HUMAN Q96P11
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UniProt:Q96P11
Recommended name：28S rRNA (cytosine-C(5))-methyltransferase
EC number：EC:2.1.1.-
Alternative names：(NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein)
Cleaved into：
GeneID：55695
Gene names (primary )：NSUN5
Gene names (synonym )：NSUN5A WBSCR20 WBSCR20A
Gene names (ORF )：
Length：429
Mass：46692
Sequence：MGLYAAAAGVLAGVESRQGSIKGLVYSSNFQNVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFSYQGRASSLDDLRALKGKHFLLDPLMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGKIFAFDLDAKRLASMATLLARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGMPSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSTCSLCQEENEDVVRDALQQNPGAFRLAPALPAWPHRGLSTFPGAEHCLRASPETTLSSGFFVAVIERVEVPR
Tissue specificity：Ubiquitous (PubMed:11978965, PubMed:12073013). Detected in placenta, heart and skeletal muscle (PubMed:11978965, PubMed:12073013). {ECO:0000269|PubMed:11978965, ECO:0000269|PubMed:12073013}.
Induction：Down-regulated in some glioma; epigenetic inactivation is a hallmark of glioma patients with long-term survival. {ECO:0000269|PubMed:31428936}.
Developmental stage：
Protein families：Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family