ZFP42_HUMAN Q96MM3
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UniProt:Q96MM3
Recommended name:Zinc finger protein 42 homolog
EC number:
Alternative names:(Zfp-42) (Reduced expression protein 1) (REX-1) (hREX-1) (Zinc finger protein 754)
Cleaved into:
GeneID:132625
Gene names (primary ):ZFP42
Gene names (synonym ):REX1 ZNF754
Gene names (ORF ):
Length:310
Mass:34802
Sequence:MSQQLKKRAKTRHQKGLGGRAPSGAKPRQGKSSQDLQAEIEPVSAVWALCDGYVCYEPGPQALGGDDFSDCYIECVIRGEFSQPILEEDSLFESLEYLKKGSEQQLSQKVFEASSLECSLEYMKKGVKKELPQKIVGENSLEYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARKKPPINKEYDSLSAIACPQSGCTRKLRNRAALRKHLLIHGPRDHVCAECGKAFVESSKLKRHFLVHTGEKPFRCTFEGCGKRFSLDFNLRTHVRIHTGEKRFVCPFQGCNRRFIQSNNLKAHILTHANTNKNEQEGK
Tissue specificity:Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines. {ECO:0000269|PubMed:12110702, ECO:0000269|PubMed:16344273, ECO:0000269|PubMed:16424014, ECO:0000269|PubMed:16865673}.
Induction:Down-regulated upon retinoic acid addition to F9 stem cells. {ECO:0000269|PubMed:16344273}.
Developmental stage:
Protein families:Krueppel C2H2-type zinc-finger protein family