FGL1_HUMAN   Q08830


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UniProt:Q08830

Recommended name:Fibrinogen-like protein 1

EC number:

Alternative names:(HP-041) (Hepassocin) (HPS) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1)

Cleaved into:

GeneID:2267

Gene names  (primary ):FGL1

Gene names  (synonym ):HFREP1

Gene names  (ORF ):

Length:312

Mass:36379

Sequence:MAKVFSFILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI

Tissue specificity:Under normal conditions, liver-specific. {ECO:0000269|PubMed:11470158}.

Induction:Expression is induced by interleukin-6 (IL6) (PubMed:18039467). Up-regulated in a number of cancers, such as lung cancer, prostate cancer, melanoma and colorectal cancer (PubMed:30580966). {ECO:0000269|PubMed:18039467, ECO:0000269|PubMed:30580966}.

Developmental stage:

Protein families:


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