FGL1_HUMAN Q08830
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UniProt:Q08830
Recommended name:Fibrinogen-like protein 1
EC number:
Alternative names:(HP-041) (Hepassocin) (HPS) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1)
Cleaved into:
GeneID:2267
Gene names (primary ):FGL1
Gene names (synonym ):HFREP1
Gene names (ORF ):
Length:312
Mass:36379
Sequence:MAKVFSFILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
Tissue specificity:Under normal conditions, liver-specific. {ECO:0000269|PubMed:11470158}.
Induction:Expression is induced by interleukin-6 (IL6) (PubMed:18039467). Up-regulated in a number of cancers, such as lung cancer, prostate cancer, melanoma and colorectal cancer (PubMed:30580966). {ECO:0000269|PubMed:18039467, ECO:0000269|PubMed:30580966}.
Developmental stage:
Protein families: