BLK_HUMAN   P51451


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UniProt:P51451

Recommended name:Tyrosine-protein kinase Blk

EC number:EC:2.7.10.2

Alternative names:(B lymphocyte kinase) (p55-Blk)

Cleaved into:

GeneID:640

Gene names  (primary ):BLK

Gene names  (synonym ):

Gene names  (ORF ):

Length:505

Mass:57706

Sequence:MGLVSSKKPDKEKPIKEKDKGQWSPLKVSAQDKDAPPLPPLVVFNHLTPPPPDEHLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLKGTGDWWLARSLVTGREGYVPSNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTATERQYELQP

Tissue specificity:Expressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands and hair follicles. {ECO:0000269|PubMed:19667185}.

Induction:Expression is under the control of NF-kappa-B as well as the B-cell specific transcription factors PAX5 and EBF1. {ECO:0000269|PubMed:10553071}.

Developmental stage:

Protein families:Protein kinase superfamily, Tyr protein kinase family, SRC subfamily


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