MKRN1_HUMAN Q9UHC7
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UniProt:Q9UHC7
Recommended name:E3 ubiquitin-protein ligase makorin-1
EC number:EC:2.3.2.27
Alternative names:(RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1)
Cleaved into:
GeneID:23608
Gene names (primary ):MKRN1
Gene names (synonym ):RNF61
Gene names (ORF ):
Length:482
Mass:53349
Sequence:MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
Tissue specificity:Ubiquitous. {ECO:0000269|PubMed:10843807, ECO:0000269|PubMed:16785614}.
Induction:Frequently induced in esophageal squamous cell carcinoma (SCC) tissues. {ECO:0000269|PubMed:19604354}.
Developmental stage:
Protein families: