SPI1_HUMAN   P17947


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UniProt:P17947

Recommended name:Transcription factor PU.1

EC number:

Alternative names:(31 kDa-transforming protein)

Cleaved into:

GeneID:6688

Gene names  (primary ):SPI1

Gene names  (synonym ):

Gene names  (ORF ):

Length:270

Mass:31083

Sequence:MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLAERRHPPH

Tissue specificity:

Induction:Highly expressed in both FV-P and FV-A-induced erythro-leukemia cell lines that have undergone rearrangements of the SPI1 gene due to the insertion of SFFV. Negatively regulated by microRNA-155 (miR-155). {ECO:0000269|PubMed:23166356}.

Developmental stage:

Protein families:ETS family


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