COA8_HUMAN   Q96IL0


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UniProt:Q96IL0

Recommended name:Cytochrome c oxidase assembly factor 8

EC number:

Alternative names:(COA8) (Apoptogenic protein 1, mitochondrial) (APOP-1)

Cleaved into:

GeneID:84334

Gene names  (primary ):COA8

Gene names  (synonym ):APOP1 APOPT1 C14orf153

Gene names  (ORF ):

Length:206

Mass:24153

Sequence:MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQLAPERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLRQETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRTESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQKQKKRSN

Tissue specificity:Expressed in fibroblasts. {ECO:0000269|PubMed:25175347}.

Induction:In conditions of increased oxidative stress, the protein is stabilized, increasing its mature intramitochondrial form and thereby protecting COX from oxidatively induced degradation. {ECO:0000269|PubMed:25175347, ECO:0000269|PubMed:30552096}.

Developmental stage:

Protein families:COA8 family


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