RGS1_HUMAN Q08116
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UniProt:Q08116
Recommended name:Regulator of G-protein signaling 1
EC number:
Alternative names:(RGS1) (B-cell activation protein BL34) (Early response protein 1R20)
Cleaved into:
GeneID:5996
Gene names (primary ):RGS1
Gene names (synonym ):1R20 BL34 IER1
Gene names (ORF ):
Length:209
Mass:23858
Sequence:MRAAAISTPKLDKMPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK
Tissue specificity:Detected in peripheral blood monocytes (PubMed:10480894). Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high (PubMed:8473738). {ECO:0000269|PubMed:10480894, ECO:0000269|PubMed:8473738}.
Induction:In response to several B-cell activation signals. {ECO:0000269|PubMed:8473738}.
Developmental stage:
Protein families: