PVRIG_HUMAN Q6DKI7
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UniProt:Q6DKI7
Recommended name：Transmembrane protein PVRIG
EC number：
Alternative names：(CD112 receptor) (CD112R) (Poliovirus receptor-related immunoglobulin domain-containing protein)
Cleaved into：
GeneID：79037
Gene names (primary )：PVRIG
Gene names (synonym )：C7orf15
Gene names (ORF )：
Length：326
Mass：34344
Sequence：MRTEAQVPALQPPEPGLEGAMGHRTLVLPWVLLTLCVTAGTPEVWVQVRMEATELSSFTIRCGFLGSGSISLVTVSWGGPNGAGGTTLAVLHPERGIRQWAPARQARWETQSSISLILEGSGASSPCANTTFCCKFASFPEGSWEACGSLPPSSDPGLSAPPTPAPILRADLAGILGVSGVLLFGCVYLLHLLRRHKHRPAPRLQPSRTSPQAPRARAWAPSQASQAALHVPYATINTSCRPATLDTAHPHGGPSWWASLPTHAAHRPQGPAAWASTPIPARGSFVSVENGLYAQAGERPPHTGPGLTLFPDPRGPRAMEGPLGVR
Tissue specificity：Expressed in some types of immune cells. Expressed at low levels on the surface of freshly isolated T-cells and natural killer (NK) cells, predominantly on CD8+ T-cells (mainly memory/effector, but not naive cells) and on both CD16+ and CD16- NK cells. T-cell expression levels are variable among individuals. Not detected in B-cells, naive or helper T-cells, monocytes, nor neutrophils (at protein level). Not detected in dendritic cells. {ECO:0000269|PubMed:26755705}.
Induction：In T-cells, up-regulated by activation induced by treatment with anti-CD3 and anti-CD28 antibodies. {ECO:0000269|PubMed:26755705}.
Developmental stage：
Protein families：