CBWD1_HUMAN Q9BRT8
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UniProt:Q9BRT8
Recommended name：COBW domain-containing protein 1
EC number：
Alternative names：(Cobalamin synthase W domain-containing protein 1) (COBP) (NPC-A-6 COBW domain-containing protein 1) (NPC-A-6)
Cleaved into：
GeneID：55871
Gene names (primary )：CBWD1
Gene names (synonym )：
Gene names (ORF )：
Length：395
Mass：44068
Sequence：MLPAVGSADEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNEFGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDSGLRAIENLMQKKGKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEEKPDGLINEATRQVALADAILINKTDLVPEEDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLLGRNLDKDILKQLFIATVTETEKQWTTRFQEDQVCT
Tissue specificity：Ubiquitously expressed. Up-regulated in cultured astrocytes treated with dopamine. {ECO:0000269|PubMed:15233989}.
Induction：Increased expression in response to dopamine treatment. Down-regulated by ZNF658 in response to zinc. {ECO:0000269|PubMed:11489251, ECO:0000269|PubMed:25582195}.
Developmental stage：
Protein families：SIMIBI class G3E GTPase family, CobW subfamily