CHAC1_HUMAN Q9BUX1
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UniProt:Q9BUX1
Recommended name:Glutathione-specific gamma-glutamylcyclotransferase 1
EC number:EC:4.3.2.7
Alternative names:(Gamma-GCG 1) (Blocks Notch protein) (Botch) (Cation transport regulator-like protein 1)
Cleaved into:
GeneID:79094
Gene names (primary ):CHAC1
Gene names (synonym ):BOTCH
Gene names (ORF ):
Length:222
Mass:24418
Sequence:MKQESAAPNTPPTSQSPTPSAQFPRNDGDPQALWIFGYGSLVWRPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLEDHEGCTWGVAYQVQGEQVSKALKYLNVREAVLGGYDTKEVTFYPQDAPDQPLKALAYVATPQNPGYLGPAPEEAIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLAAIVDAVGTMLPCFCPTEQALALV
Tissue specificity:
Induction:Induced by chemical activators of the unfolded protein response (UPR) such as tunicamycin, DTT and thapsigargin. {ECO:0000269|PubMed:19109178}.
Developmental stage:
Protein families:Gamma-glutamylcyclotransferase family, ChaC subfamily