LEP_HUMAN   P41159


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UniProt:P41159

Recommended name:Leptin

EC number:

Alternative names:(Obese protein) (Obesity factor)

Cleaved into:

GeneID:3952

Gene names  (primary ):LEP

Gene names  (synonym ):OB OBS

Gene names  (ORF ):

Length:167

Mass:18641

Sequence:MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC

Tissue specificity:Adipose tissue is the main source of leptin. It is also produced by other peripheral tissues such as the skeletal muscle (PubMed:7789654, PubMed:16052473, PubMed:12448771). Expressed by intercalated and striated tracts of submandibular and parotid salivary gland intralobular ducts (PubMed:12448771). Detected by fundic epithelium of the gastric mucosa (PubMed:10896907). Secreted into blood and gastric juice (PubMed:10896907). {ECO:0000269|PubMed:10896907, ECO:0000269|PubMed:12448771, ECO:0000269|PubMed:16052473, ECO:0000269|PubMed:7789654}.

Induction:Induced by secretin. {ECO:0000269|PubMed:10896907}.

Developmental stage:

Protein families:Leptin family


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