DERM_HUMAN Q07507
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UniProt:Q07507
Recommended name:Dermatopontin
EC number:
Alternative names:(Tyrosine-rich acidic matrix protein) (TRAMP)
Cleaved into:
GeneID:1805
Gene names (primary ):DPT
Gene names (synonym ):
Gene names (ORF ):
Length:201
Mass:24005
Sequence:MDLSLLWVLLPLVTMAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV
Tissue specificity:Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts. {ECO:0000269|PubMed:10233760, ECO:0000269|PubMed:8104875}.
Induction:Induced by TGFB1, repressed by IL4/interleukin-4. {ECO:0000269|PubMed:10233760}.
Developmental stage:
Protein families:Dermatopontin family