PTGES_HUMAN   O14684


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UniProt:O14684

Recommended name:Prostaglandin E synthase

EC number:EC:5.3.99.3

Alternative names:(Glutathione peroxidase PTGES) (Glutathione transferase PTGES) (Microsomal glutathione S-transferase 1-like 1) (MGST1-L1) (Microsomal prostaglandin E synthase 1) (MPGES-1) (p53-induced gene 12 protein)

Cleaved into:

GeneID:9536

Gene names  (primary ):PTGES

Gene names  (synonym ):MGST1L1 MPGES1 PGES PIG12

Gene names  (ORF ):

Length:152

Mass:17102

Sequence:MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL

Tissue specificity:

Induction:Induced by the interleukin IL1B (PubMed:10377395, PubMed:10760517). Induced By p53/TP53 (PubMed:9305847). {ECO:0000269|PubMed:10377395, ECO:0000269|PubMed:10760517, ECO:0000269|PubMed:9305847}.

Developmental stage:

Protein families:MAPEG family


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