PTGES_HUMAN O14684
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UniProt:O14684
Recommended name:Prostaglandin E synthase
EC number:EC:5.3.99.3
Alternative names:(Glutathione peroxidase PTGES) (Glutathione transferase PTGES) (Microsomal glutathione S-transferase 1-like 1) (MGST1-L1) (Microsomal prostaglandin E synthase 1) (MPGES-1) (p53-induced gene 12 protein)
Cleaved into:
GeneID:9536
Gene names (primary ):PTGES
Gene names (synonym ):MGST1L1 MPGES1 PGES PIG12
Gene names (ORF ):
Length:152
Mass:17102
Sequence:MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
Tissue specificity:
Induction:Induced by the interleukin IL1B (PubMed:10377395, PubMed:10760517). Induced By p53/TP53 (PubMed:9305847). {ECO:0000269|PubMed:10377395, ECO:0000269|PubMed:10760517, ECO:0000269|PubMed:9305847}.
Developmental stage:
Protein families:MAPEG family