IL17_HUMAN Q16552
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UniProt:Q16552
Recommended name:Interleukin-17A
EC number:
Alternative names:(IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Cleaved into:
GeneID:3605
Gene names (primary ):IL17A
Gene names (synonym ):CTLA8 IL17
Gene names (ORF ):
Length:155
Mass:17504
Sequence:MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
Tissue specificity:Expressed in memory Th17 cells (at protein level). {ECO:0000269|PubMed:17763419}.
Induction:Induced upon differentiation of CD4-positive T cells. Up-regulated by IL23A-IL12B (PubMed:17763419). Up-regulated in peripheral blood mononuclear cells upon West Nile virus infection (PubMed:27795421). {ECO:0000269|PubMed:17763419, ECO:0000269|PubMed:27795421}.
Developmental stage:
Protein families:IL-17 family