5NT3A_HUMAN Q9H0P0
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UniProt:Q9H0P0
Recommended name:Cytosolic 5'-nucleotidase 3A
EC number:EC:3.1.3.5
Alternative names:(7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36)
Cleaved into:
GeneID:51251
Gene names (primary ):NT5C3A
Gene names (synonym ):NT5C3 P5N1 UMPH1
Gene names (ORF ):HSPC233
Length:336
Mass:37948
Sequence:MRAPSMDRAAVARVGAVASASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQDESLEVANSILQKIL
Tissue specificity:Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver. {ECO:0000269|PubMed:11369620, ECO:0000269|PubMed:15238149}.
Induction:Isoform 2 is induced by interferon alpha in Raji cells in association with lupus inclusions. {ECO:0000269|PubMed:8557639}.
Developmental stage:
Protein families:Pyrimidine 5'-nucleotidase family