5NT3A_HUMAN   Q9H0P0


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UniProt:Q9H0P0

Recommended name:Cytosolic 5'-nucleotidase 3A

EC number:EC:3.1.3.5

Alternative names:(7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36)

Cleaved into:

GeneID:51251

Gene names  (primary ):NT5C3A

Gene names  (synonym ):NT5C3 P5N1 UMPH1

Gene names  (ORF ):HSPC233

Length:336

Mass:37948

Sequence:MRAPSMDRAAVARVGAVASASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQDESLEVANSILQKIL

Tissue specificity:Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver. {ECO:0000269|PubMed:11369620, ECO:0000269|PubMed:15238149}.

Induction:Isoform 2 is induced by interferon alpha in Raji cells in association with lupus inclusions. {ECO:0000269|PubMed:8557639}.

Developmental stage:

Protein families:Pyrimidine 5'-nucleotidase family


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