LRAT_HUMAN O95237
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UniProt:O95237
Recommended name：Lecithin retinol acyltransferase
EC number：EC:2.3.1.135
Alternative names：(Phosphatidylcholine--retinol O-acyltransferase)
Cleaved into：
GeneID：9227
Gene names (primary )：LRAT
Gene names (synonym )：
Gene names (ORF )：
Length：230
Mass：25703
Sequence：MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG
Tissue specificity：Hepatic stellate cells and endothelial cells (at protein level). Found at high levels in testis and liver, followed by retinal pigment epithelium, small intestine, prostate, pancreas and colon. Low expression observed in brain. In fetal tissues, expressed in retinal pigment epithelium and liver, and barely in the brain. {ECO:0000269|PubMed:18544127, ECO:0000269|PubMed:9920938}.
Induction：LRAT activity is up-regulated by dietary vitamin A. Under conditions of vitamin A depletion, LRAT expression in the liver is induced by retinoic acid (By similarity). {ECO:0000250}.
Developmental stage：
Protein families：H-rev107 family