DRAM2_HUMAN Q6UX65
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UniProt:Q6UX65
Recommended name:DNA damage-regulated autophagy modulator protein 2
EC number:
Alternative names:(Transmembrane protein 77)
Cleaved into:
GeneID:128338
Gene names (primary ):DRAM2
Gene names (synonym ):TMEM77
Gene names (ORF ):PSEC0031 UNQ154/PRO180
Length:266
Mass:29766
Sequence:MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI
Tissue specificity:Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Expressed in the retina. Not detected in brain or thymus. {ECO:0000269|PubMed:19556885, ECO:0000269|PubMed:19895784, ECO:0000269|PubMed:25983245}.
Induction:Not induced by p53/TP53 or TP73/p73. {ECO:0000269|PubMed:19556885}.
Developmental stage:
Protein families:DRAM/TMEM150 family