DRAM2_HUMAN   Q6UX65


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UniProt:Q6UX65

Recommended name:DNA damage-regulated autophagy modulator protein 2

EC number:

Alternative names:(Transmembrane protein 77)

Cleaved into:

GeneID:128338

Gene names  (primary ):DRAM2

Gene names  (synonym ):TMEM77

Gene names  (ORF ):PSEC0031 UNQ154/PRO180

Length:266

Mass:29766

Sequence:MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI

Tissue specificity:Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Expressed in the retina. Not detected in brain or thymus. {ECO:0000269|PubMed:19556885, ECO:0000269|PubMed:19895784, ECO:0000269|PubMed:25983245}.

Induction:Not induced by p53/TP53 or TP73/p73. {ECO:0000269|PubMed:19556885}.

Developmental stage:

Protein families:DRAM/TMEM150 family


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