AK1BA_HUMAN   O60218


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UniProt:O60218

Recommended name:Aldo-keto reductase family 1 member B10

EC number:EC:1.1.1.300

Alternative names:(ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase)

Cleaved into:

GeneID:57016

Gene names  (primary ):AKR1B10

Gene names  (synonym ):AKR1B11

Gene names  (ORF ):

Length:316

Mass:36020

Sequence:MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFNAEY

Tissue specificity:Found in many tissues. Highly expressed in small intestine, colon and adrenal gland. {ECO:0000269|PubMed:9565553}.

Induction:Overexpressed in certain types of cancers, including hepatocellular carcinoma and lung cancer associated with tobacco smoking. {ECO:0000269|PubMed:15755999, ECO:0000269|PubMed:9565553}.

Developmental stage:

Protein families:Aldo/keto reductase family


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