AK1BA_HUMAN O60218
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UniProt:O60218
Recommended name:Aldo-keto reductase family 1 member B10
EC number:EC:1.1.1.300
Alternative names:(ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase)
Cleaved into:
GeneID:57016
Gene names (primary ):AKR1B10
Gene names (synonym ):AKR1B11
Gene names (ORF ):
Length:316
Mass:36020
Sequence:MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFNAEY
Tissue specificity:Found in many tissues. Highly expressed in small intestine, colon and adrenal gland. {ECO:0000269|PubMed:9565553}.
Induction:Overexpressed in certain types of cancers, including hepatocellular carcinoma and lung cancer associated with tobacco smoking. {ECO:0000269|PubMed:15755999, ECO:0000269|PubMed:9565553}.
Developmental stage:
Protein families:Aldo/keto reductase family