SIR7_HUMAN Q9NRC8
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UniProt:Q9NRC8
Recommended name:NAD-dependent protein deacetylase sirtuin-7
EC number:EC:2.3.1.286
Alternative names:(NAD-dependent protein deacylase sirtuin-7) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Cleaved into:
GeneID:51547
Gene names (primary ):SIRT7
Gene names (synonym ):SIR2L7
Gene names (ORF ):
Length:400
Mass:44898
Sequence:MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
Tissue specificity:
Induction:Overexpressed in thyroid carcinoma cell lines and tissues, but not in adenomas. {ECO:0000269|PubMed:11953824}.
Developmental stage:
Protein families:Sirtuin family, Class IV subfamily