SIR7_HUMAN   Q9NRC8


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UniProt:Q9NRC8

Recommended name:NAD-dependent protein deacetylase sirtuin-7

EC number:EC:2.3.1.286

Alternative names:(NAD-dependent protein deacylase sirtuin-7) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)

Cleaved into:

GeneID:51547

Gene names  (primary ):SIRT7

Gene names  (synonym ):SIR2L7

Gene names  (ORF ):

Length:400

Mass:44898

Sequence:MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT

Tissue specificity:

Induction:Overexpressed in thyroid carcinoma cell lines and tissues, but not in adenomas. {ECO:0000269|PubMed:11953824}.

Developmental stage:

Protein families:Sirtuin family, Class IV subfamily


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