PCKGC_HUMAN   P35558


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UniProt:P35558

Recommended name:Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

EC number:EC:4.1.1.32

Alternative names:(PEPCK-C) (Serine-protein kinase PCK1)

Cleaved into:

GeneID:5105

Gene names  (primary ):PCK1

Gene names  (synonym ):PEPCK1

Gene names  (ORF ):

Length:622

Mass:69195

Sequence:MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRISQM

Tissue specificity:Major sites of expression are liver, kidney and adipocytes. {ECO:0000269|PubMed:8490617}.

Induction:Regulated by cAMP and insulin. {ECO:0000269|PubMed:1656199}.

Developmental stage:

Protein families:Phosphoenolpyruvate carboxykinase [GTP] family


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