PCKGC_HUMAN P35558
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UniProt:P35558
Recommended name:Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
EC number:EC:4.1.1.32
Alternative names:(PEPCK-C) (Serine-protein kinase PCK1)
Cleaved into:
GeneID:5105
Gene names (primary ):PCK1
Gene names (synonym ):PEPCK1
Gene names (ORF ):
Length:622
Mass:69195
Sequence:MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRISQM
Tissue specificity:Major sites of expression are liver, kidney and adipocytes. {ECO:0000269|PubMed:8490617}.
Induction:Regulated by cAMP and insulin. {ECO:0000269|PubMed:1656199}.
Developmental stage:
Protein families:Phosphoenolpyruvate carboxykinase [GTP] family