HUNIN_HUMAN   Q8IVG9


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UniProt:Q8IVG9

Recommended name:Humanin

EC number:

Alternative names:(Humanin mitochondrial) (HNM)

Cleaved into:

GeneID:

Gene names  (primary ):MT-RNR2

Gene names  (synonym ):HN

Gene names  (ORF ):

Length:24

Mass:2687

Sequence:MAPRGFSCLLLLTSEIDLPVKRRA

Tissue specificity:Expressed in the heart, skeletal muscles, kidney and liver. Lesser but significant expression is observed in the brain and the gastrointestinal tract. Expressed in the AD brain, where it is found in some of the large intact neurons of the occipital lobes and small and round reactive glial cells in the hippocampus. {ECO:0000269|PubMed:11371646, ECO:0000269|PubMed:12009529, ECO:0000269|PubMed:19477263}.

Induction:Release is regulated by intracellular mechanism. The intracellular level is regulated by TRIM11 through proteasome-mediated degradation. {ECO:0000269|PubMed:19477263}.

Developmental stage:

Protein families:Humanin family


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