PERF_HUMAN P14222
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UniProt:P14222
Recommended name：Perforin-1
EC number：
Alternative names：(P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Cleaved into：
GeneID：5551
Gene names (primary )：PRF1
Gene names (synonym )：PFP
Gene names (ORF )：
Length：555
Mass：61377
Sequence：MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFPVDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREALRRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQMLLGEPPGNRSGAVW
Tissue specificity：
Induction：Repressed by contact with target cells. {ECO:0000269|PubMed:8676885}.
Developmental stage：
Protein families：Complement C6/C7/C8/C9 family