IMDH2_HUMAN P12268
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UniProt:P12268
Recommended name：Inosine-5'-monophosphate dehydrogenase 2
EC number：EC:1.1.1.205
Alternative names：(IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (IMPDH-II)
Cleaved into：
GeneID：3615
Gene names (primary )：IMPDH2
Gene names (synonym )：IMPD2
Gene names (ORF )：
Length：514
Mass：55805
Sequence：MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
Tissue specificity：IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
Induction：Selectively up-regulated in neoplastic and replicating cells.
Developmental stage：
Protein families：IMPDH/GMPR family