OLA1_HUMAN   Q9NTK5


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UniProt:Q9NTK5

Recommended name:Obg-like ATPase 1

EC number:

Alternative names:(DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9)

Cleaved into:

GeneID:29789

Gene names  (primary ):OLA1

Gene names  (synonym ):GTPBP9

Gene names  (ORF ):PRO2455 PTD004

Length:396

Mass:44744

Sequence:MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK

Tissue specificity:Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus.

Induction:Strongly down-regulated by DNA damage-inducing agents. {ECO:0000269|PubMed:20053727}.

Developmental stage:

Protein families:TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family, YchF/OLA1 subfamily


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