SGPP2_HUMAN Q8IWX5
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UniProt:Q8IWX5
Recommended name：Sphingosine-1-phosphate phosphatase 2
EC number：EC:3.1.3.-
Alternative names：(SPPase2) (Spp2) (hSPP2) (Sphingosine-1-phosphatase 2)
Cleaved into：
GeneID：130367
Gene names (primary )：SGPP2
Gene names (synonym )：
Gene names (ORF )：
Length：399
Mass：44741
Sequence：MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP
Tissue specificity：Expressed strongly in kidney and heart, followed by brain, colon, small intestine and lung. Not detected in skeletal muscle, thymus, spleen, liver, placenta, and peripheral blood leukocytes. {ECO:0000269|PubMed:12411432}.
Induction：Strongly induced by TNF, also induced by bacterial lipopolycaccharides (LPS) in neutrophils, endothelial cells, and other cell types. Not induced by growth-related factors. {ECO:0000269|PubMed:17113265}.
Developmental stage：
Protein families：Type 2 lipid phosphate phosphatase family