PTPRE_HUMAN   P23469


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UniProt:P23469

Recommended name:Receptor-type tyrosine-protein phosphatase epsilon

EC number:EC:3.1.3.48

Alternative names:(Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon)

Cleaved into:

GeneID:5791

Gene names  (primary ):PTPRE

Gene names  (synonym ):

Gene names  (ORF ):

Length:700

Mass:80642

Sequence:MEPLCPLLLVGFSLPLARALRGNETTADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLLVLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK

Tissue specificity:Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells). {ECO:0000269|PubMed:8610169}.

Induction:Up-regulated by 12-O-tetradecanoylphorbol-13-acetate (TPA) in HL-60 cells. {ECO:0000269|PubMed:8618876}.

Developmental stage:

Protein families:Protein-tyrosine phosphatase family, Receptor class 4 subfamily


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