ACER1_HUMAN   Q8TDN7


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UniProt:Q8TDN7

Recommended name:Alkaline ceramidase 1

EC number:EC:3.5.1.-

Alternative names:(AlkCDase 1) (Alkaline CDase 1) (Acylsphingosine deacylase 3) (N-acylsphingosine amidohydrolase 3)

Cleaved into:

GeneID:125981

Gene names  (primary ):ACER1

Gene names  (synonym ):ASAH3

Gene names  (ORF ):

Length:264

Mass:31095

Sequence:MPSIFAYQSSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQFIRLVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWISDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKVRYWPRDSWPVGLPYVEIRGDDKDC

Tissue specificity:Mainly expressed in epidermis. {ECO:0000269|PubMed:16477081, ECO:0000269|PubMed:17713573}.

Induction:Up-regulated by Ca(2+) (PubMed:17713573). Down-regulated by epidermal growth factor/EGF (PubMed:17713573). {ECO:0000269|PubMed:17713573}.

Developmental stage:

Protein families:Alkaline ceramidase family


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