SUSD6_HUMAN Q92537
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UniProt:Q92537
Recommended name:Sushi domain-containing protein 6
EC number:
Alternative names:(Drug-activated gene overexpressed protein)
Cleaved into:
GeneID:9766
Gene names (primary ):SUSD6
Gene names (synonym ):DRAGO KIAA0247
Gene names (ORF ):
Length:303
Mass:32090
Sequence:MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLLKEA
Tissue specificity:
Induction:Up-regulated by chemotherapeutic DNA-damaging agents and by p53/TP53 and/or by p73/TP73 in response to cytotoxic insults (PubMed:24652652). Up-regulated by lipopolysaccharide (LPS) in monocytic THP1 cells (PubMed:20236627). Up-regulated in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. {ECO:0000269|PubMed:20236627, ECO:0000269|PubMed:24652652}.
Developmental stage:
Protein families: